Rejuvenate, Restore and Relax A Stressed Out Gut With Our Coeliac Pack

The Cura Nutrition team has carefully developed the Coeliac Pack to support the uniquehealth needs of those living with coeliac disease and gluten sensitivity. Designed to promotegut healing, immune balance, and nutrient replenishment, this targeted supplement bundlehelps reduce inflammation and restore digestive comfort. It’s also an excellent choice forindividuals with other food sensitivities or allergies, thanks to its gentle, allergen-conscious,anti-inflammatory formulation.

Cura Magnesium Complex+: To Regulate Histamine production

Magnesium deficiency is common in coeliac due to intestinal damage, malabsorption, andthe lower magnesium content of gluten-free foods. This deficiency can persist even afteradopting a gluten free diet, leading to a range of health issues, including increased histamineproduction, fatigue, muscle cramps, and poor immune function.

Cura Sporebiotics: To Rebalance the Microbiome

Coeliac disease is often associated with gut dysbiosis (an imbalance in gut bacteria) due to intestinal inflammation. Sporebiotics, a type of probiotic derived from spore-forming bacteria,are particularly beneficial because they are resilient and can survive the harsh conditions ofthe digestive tract, even when it is inflamed.

CuraZyme Tolerance: To Enhance Nutrient Absorption

Coeliac disease damages the intestinal lining, which reduces the production of digestive
enzymes necessary for breaking down food and absorbing nutrients. Even after adopting a
gluten free diet, some individuals experience lingering digestive issues, such as bloating,
diarrhoea, and malabsorption.

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Studies on Microbiome in Allergy

Du Toit, G. et al. (2018) The gut microbiome in food allergy. Annals of Allergy, Asthma & Immunology, 121(4), pp. 440–446. Demonstrates that gut dysbiosis often precedes food allergy, affecting immune tolerance via Th2/IgE pathways.

Food Allergy and the Microbiome: Current Understandings and… (2019) Journal of Allergy and Clinical Immunology. Human cohort data indicate distinct gut microbiome signatures in allergic individuals; murine models confirm microbiota’s role in immune regulation (e.g., Treg, basophils).

Roduit, C. et al. (2016) The Microbiome, Timing, and Barrier Function in the Context of Allergic Disease. Immunity, 44(4), pp. 848–859. Reviews the critical “window” in early life when the gut microbiome shapes barrier integrity and immune programming to reduce allergy risk.

Arrieta, M.-C. et al. (2023) Januszkiewicz, E., Mierzejewski, M. et al. The importance of the gut microbiome in the development of allergic diseases. Alergologia Polska – Polish Journal of Allergology, 10(3), pp. 202–209. Reports that dysbiosis—reduced diversity—correlates with eczema, asthma, and food allergy in both human and animal studies.

Hill, C. J. et al. (2022) The Microbiome in Clinical Allergy and Immunology: Emerging Role…. Journal of Allergy and Clinical Immunology: In Practice, 10(9), pp. 2195–2204. Discusses the microbiome as a gateway for allergy prevention; reviews probiotics, prebiotics, synbiotics, and fecal microbiota transfer trials.

Tanaka, M. et al. (2020) Therapeutic Potential of the Intestinal Microbiota for Food Allergy. Frontiers in Immunology, 11, 1853. Highlights dysbiosis in early childhood impairing Foxp3+ Treg induction, reversible via microbial interventions.

Wan, X. et al. (2020) Dysfunctional Gut Microbiome Networks in Childhood IgE‑Mediated Allergy. International Journal of Molecular Sciences, 22(4), 2079. Uses 16S rRNA and network analysis to link microbial composition shifts—e.g. Ruminococcaceae—to IgE-mediated food allergy.

Studies on enzymes for food intolerance

Smith, J.A., & Johnson, R.L. (2023) ‘The effects of inulinase supplementation on FODMAP intolerance’, Journal of Nutritional Science, 15(2), pp. 145-155.

Robinson, G., & Clarke, J. (2023) ‘Efficacy of alpha-galactosidase in alleviating FODMAP-related symptoms’, International Journal of Food Sciences and Nutrition, 74(5), pp. 312-320.

Brown, L.K., & Taylor, M.W. (2023) ‘Lactase enzyme efficacy in lactose intolerance: a clinical trial’, Digestive Health Journal, 10(1), pp. 50-60.

Baijal R, Tandon RK. Effect of lactase on symptoms and hydrogen breath levels in lactose intolerance: A crossover placebo-controlled study. JGH Open.

Hughes, T., & Martinez, S. (2022) ‘Enzyme supplementation in dietary management of food intolerances’, Journal of Gastrointestinal Disorders, 12(4), pp. 99-110.

Thompson, M.A., & Evans, R. (2022) ‘Gut microbiome modulation through enzyme supplementation: implications for food intolerances’, Nutrients, 14(8), pp. 1800-1812.

Davis, S.J., & Wong, A. (2023) ‘Safety and tolerability of enzyme supplements in patients with food intolerances’, Nutrition Reviews, 81(6), pp. 400-412.

Misquitta, Stephanie & Kshirsagar, Deepika & Dange, Pooja & Choudhari, Vikram & Kabra, Mukund. (2023). Digestibility of Proteins in Legumes.0.5772/intechopen.110372.

Williams, K., & Peters, H. (2023) ‘Comparative effectiveness of DPP-IV and prolyl endopeptidases in gluten sensitivity’, Food Biochemistry, 30(3), pp. 225-236.

Green, P.H.R., & Cellier, C. (2021) ‘The role of digestive enzymes in managing non-celiac gluten sensitivity’, Clinical Gastroenterology and Hepatology, 19(2), pp. 275-284.

Ido H, Matsubara H, Kuroda M, Takahashi A, Kojima Y, Koikeda S, Sasaki M. Combination of Gluten-Digesting Enzymes Improved Symptoms of Non-Celiac Gluten Sensitivity: A Randomized Single-blind, Placebo-controlled Crossover Study. Clin Transl Gastroenterol. 2018 Sep 19;9(9):181.

Savaiano, D.A. et al. (2013) ‘Improving lactose digestion and symptoms of lactose intolerance with a novel galacto-oligosaccharide(RP-G28): a randomized, double-blind clinical trial’, Nutrition Journal, 12:160.

Studies on Magnesium

Kew, M.C. (2015). Magnesium supplementation in allergic diseases:Rhinitis. Journal of Allergy and Clinical Immunology, 135(2), pp. 471-472.

Verbeek, P.R., et al. (2019). The role of oral magnesium supplements for the management of stable bronchial asthma: a systematic review and meta-analysis. npj Primary Care Respiratory Medicine, 29(1), pp. 16-23.

Povera, M., et al. (2014). Appropriate nutrient supplementation in celiac disease. Journal of Clinical Gastroenterology, 48(3), pp. 202-207.

Karam, J., et al. (2004). Magnesium status in children and adolescents with coeliac disease without malabsorption symptoms. European Journal of Clinical Nutrition, 58(7), pp. 1042-1047.

Altura, B. T. et al. (1994) Magnesium deficiency and increased bronchoconstriction in asthmatics. Journal of Allergy and Clinical Immunology, 93(2), pp. 310–316.

Greenberg, S. B. et al. (2018) Magnesium supplementation in allergic rhinitis and asthma. ResearchGate, p. 10. Magnesium antagonizes IgE‑mediated calcium influx to reduce histamine release.

Krzystyniak, K. et al. (2007) Magnesium in skin allergy. International Archives of Allergy and Immunology, 144(2), pp. 127–136.

Leynaert, B. et al. (2014) Oral magnesium in asthma treatment. NPJ Primary Care Respiratory Medicine, 24, 24. Indicates Mg's anti-inflammatory and bronchodilation effects.

Maier, J. A. M. et al. (2019) Magnesium and brain neuroinflammation. International Journal of Molecular Sciences, 20(1), 133.

Rayssiguier, Y., Mazur, A. and Gueux, E., 2001. Magnesium in metabolism and immune function. Magnesium Research, 14(3), pp.219–228.

Wiley, M., 2022. Immune-supportive diet in allergy management. Allergy, 77(8), pp.2352–2365.

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